Ringkasan :
Drug discovery research into the two types of chemotherapeutic agents, antimicrobials and anticancer, is an ongoing process, due to increasing resistance to these agents leading to subsequent failure of the treatment. This continues to challenge the pharmaceutical industry in developing newer antibiotics or safer antineoplastic agents. Medicinal Chemistry of Chemotherapeutic Agents focuses on the basics and fundamentals of chemistry involved in the chemotherapeutic agents. Each chapter comprises the distinct chemical classifications with structure and IUPAC nomenclature, synthetic schemes and routes for each drug, mechanism of the drug action, metabolic pathway and structure-activity relationship (SAR) studies. It covers the current research focused on the drug resistance and the methods to overcome it, development of newer drugs belonging to each category of the chemotherapeutic agents, molecules currently under clinical trials and newly approved drugs, if any.

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