Bone regeneration in dehiscence-type defects at chemically modified (SLActives) and conventional SLA titanium implants: a pilot study in dogs
Author
: Frank Schwarz, Monika Herten
Publisher
: Blackwell Synergy
Summary :Objectives: The aim of the present study was to evaluate bone regeneration in
dehiscence-type defects at titanium implants with chemically modified (mod) and
conventional sand-blasted/acid-etched (SLA) surfaces.
Material and Methods: Standardized buccal dehiscence defects (height: 3 mm,
width: 3 mm) were surgically created following implant site preparation in both the
upper and lower jaws of four beagle dogs. modSLA and SLA implants were inserted
bilaterally according to a split-mouth design. The animals were sacrificed after 2 and
12 weeks (n52 animals each). Dissected blocks were processed for histomorphometrical
analysis: defect length, new bone height (NBH), percent linear fill (PLF),
percent of bone-to-implant contact (BIC-D) and area of new bone fill (BF).
Results: Wound healing at SLA implants was predominantly characterized by the
formation of a dense connective tissue at 2 and 12 weeks, without significant increases
in mean NBH, PLF, BIC-D or BF values. In contrast, modSLA implants exhibited a
complete defect fill at 12 weeks following implant placement. In particular,
histomorphometrical analysis revealed the following mean values at 12 weeks: NBH
(3.2 0.3 mm), PLF (98%), BIC-D (82%) and BF (2.3 0.4mm2).
Conclusion: Within the limits of the present study, it was concluded that modSLA
titanium surfaces may promote bone regeneration in acute-type buccal dehiscence
defects at submerged implants.
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